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Four crewmembers departed the International Space Station on Wednesday after a medical issue prompted their mission to be cut a month short -- a first for the orbiting laboratory.

Don't say the c-word.

US President Donald Trump said Wednesday he had held a "long call" with Venezuela's interim president Delcy Rodriguez, the first known contact between the two leaders since the ouster of Nicolas Maduro.

Real Madrid fell to a shock 3-2 defeat in the Copa del Rey last 16 on Wednesday as Alvaro Arbeloa's debut as coach ended in humiliation by second-tier opposition.

US President Donald Trump said Wednesday he had been told the killings of protesters in Iran had been halted, even as Washington moved to reduce its footprint at a major US military base in Qatar amid mounting pressure in its standoff with Tehran.

Arsenal ruined Chelsea manager Liam Rosenior's first home game as they moved closer to Wembley with a 3-2 win in the League Cup semi-final first leg on Wednesday.

Wall Street stocks fell again Wednesday as investors shrugged off solid bank earnings and US data while oil prices jumped on rising tensions between Washington and Tehran.

Inter Milan moved six points clear at the top of Serie A on Wednesday after beating Lecce 1-0 and taking advantage of Napoli's goalless draw with Parma.

Bayern Munich came from a goal down to win 3-1 at Cologne on Wednesday and restore their 11-point lead atop the Bundesliga table.

Sadio Mane scored a 78th-minute winner to give Senegal a 1-0 victory over Egypt on Wednesday in their Africa Cup of Nations semi-final in Tangiers, then said he was playing in the tournament for the last time.

US President Donald Trump held open the possibility Wednesday for a resolution on his designs over Greenland after Denmark's top diplomat said he failed to change the administration's mind on wanting to conquer the island.

The promoters of Bridgerton, the most English of TV series, chose Paris Wednesday to launch the fourth series of the hit show whose key plotline promises to be "Cinderella with a twist", according to star Yerin Ha.

California launched an investigation Wednesday into Elon Musk's xAI after its Grok chatbot generated sexualized images of women and children, as European officials said they were assessing corrective measures promised by the company.

Four crewmembers aboard the International Space Station were set to depart Wednesday after a medical issue prompted their mission to be cut a month short -- a first for the orbiting laboratory.

Napoli risk further falling behind Serie A leaders Inter Milan after being held to a goalless draw by Parma on Wednesday.

President Ahmed al-Sharaa repeated calls on Wednesday for Syria's Kurds to integrate into the state, as the army deployed reinforcements near a Kurdish-held area east of Aleppo following deadly clashes in the city.

Denmark's top diplomat said Wednesday he failed to change the mind of US President Donald Trump's administration on his threats to seize Greenland after flying to the White House for talks.

Venezuela's interim president Delcy Rodriguez declared Wednesday her country was entering a new era marked by greater tolerance towards political rivals, following the US ouster of her former boss Nicolas Maduro.

Sadio Mane scored a 78th-minute winner to give Senegal a 1-0 victory over Egypt on Wednesday in their Africa Cup of Nations semi-final in Tangiers.

UK police on Wednesday admitted "mistakes" over the decision to ban Maccabi Tel Aviv fans from a Europa League football match against Aston Villa in Birmingham, as calls mounted for the under-fire local chief constable to be sacked.

Anthony Joshua's promoter believes the former world heavyweight champion will eventually box again following a fatal car crash in Nigeria that killed two of his close friends.

California on Wednesday began investigating whether Elon Musk's artificial intelligence chatbot Grok has been letting users turn pictures of women and girls into salacious images.

Wales suffered a fresh blow on Wednesday after it was announced veteran No 8 Taulupe Faletau would miss the opening three rounds of the Six Nations with a calf problem.

Denmark and Greenland's top diplomats held high-stakes talks Wednesday at the White House, with no immediate signs of a breakthrough on President Donald Trump's threats to take control of the Arctic island.

Fin Smith could miss England's Six Nations opener against Wales next month because of a calf injury.

Don't say the c-word.

Venezuela has freed 15 journalists, including a leading opposition figure, as the slow release of political prisoners begun after Nicolas Maduro's ouster continues, activists said Wednesday.

Shaun Wane stepped down as England rugby league head coach with immediate effect on Wednesday.

Iran warned the United States on Wednesday that it was capable of responding to any attack, as Washington appeared to be pulling personnel out of a base that Iran targeted in a strike last year.

Oil prices rose further Wednesday on the political instability in major crude producer Iran and the possibility of a US intervention, which also helped push safe-haven gold to a new record high while weighing on the dollar.

On the eve of the first regular season NBA game in Germany, European basketball pioneer Detlef Schrempf is "proud" of the role he played in making the league a worldwide phenomenon.

Denmark and Greenland's top diplomats held high-stakes talks at the White House on Wednesday, with President Donald Trump warning it was "vital" for the United States to take control of the Arctic island.