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Australia holds first funerals for Bondi Beach attack victims
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Trump has 'alcoholic's personality,' chief of staff says in bombshell interview
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Rob Reiner killing: son to be charged with double murder
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Chelsea battle into League Cup semis to ease pressure on Maresca
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Netflix boss promises Warner Bros films would still be seen in cinemas
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Grok spews misinformation about deadly Australia shooting
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Stocks mostly retreat on US jobs, oil drops on Ukraine hopes
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Artificial snow woes for Milan-Cortina Winter Olympics organisers
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Trump imposes full travel bans on seven more countries, Palestinians
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New Chile leader calls for end to Maduro 'dictatorship'
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Shiffrin extends slalom domination with Courchevel win
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Doctor sentenced for supplying ketamine to 'Friends' star Perry
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Tepid 2026 outlook dents Pfizer shares
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Rob Reiner murder: son not medically cleared for court
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FIFA announces $60 World Cup tickets for 'loyal fans'
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Dembele and Bonmati scoop FIFA Best awards
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Shiffrin dominates first run in Courchevel slalom
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EU weakens 2035 combustion-engine ban to boost car industry
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Arctic sees unprecedented heat as climate impacts cascade
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French lawmakers adopt social security budget, suspend pension reform
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Afrikaners mark pilgrimage day, resonating with their US backers
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Lawmakers grill Trump officials on US alleged drug boat strikes
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Hamraoui loses case against PSG over lack of support after attack
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Trump - a year of ruling by executive order
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Iran refusing to allow independent medical examination of Nobel winner: family
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Brazil megacity Sao Paulo struck by fresh water crisis
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Australia's Green becomes most expensive overseas buy in IPL history
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VW stops production at German site for first time
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Man City star Doku sidelined until new year
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Rome's new Colosseum station reveals ancient treasures
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EU eases 2035 combustion-engine ban to boost car industry
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'Immense' collection of dinosaur footprints found in Italy
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US unemployment rises further, hovering at highest since 2021
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Senators grill Trump officials on US alleged drug boat strikes
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Filmmaker Rob Reiner's son to be formally charged with parents' murder
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Shift in battle to tackle teens trapped in Marseille drug 'slavery'
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Stocks retreat on US jobs, oil drops on Ukraine hopes
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Manchester United 'wanted me to leave', claims Fernandes
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Serbian President blames 'witch hunt' for ditched Kushner hotel plan
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Man who hit Liverpool parade jailed for over 21 years
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Sahel juntas would have welcomed a coup in Benin: analysts
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PSG ordered to pay around 60mn euros to Mbappe in wage dispute
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BBC says will fight Trump's $10 bn defamation lawsuit
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Stocks retreat ahead of US jobs, oil drops on Ukraine hopes
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Suicide bomber kills five soldiers in northeast Nigeria: sources
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EU set to drop 2035 combustion-engine ban to boost car industry
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Australia's Green sold for record 252 mn rupees in IPL auction
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Elusive December sun leaves Stockholm in the dark
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Brendan Rodgers joins Saudi club Al Qadsiah
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Thailand says Cambodia must announce ceasefire 'first' to stop fighting
Tepid 2026 outlook dents Pfizer shares
Pfizer signaled Tuesday it expects a challenging 2026 as it invests in new products to offset declines in Covid-19 revenues while limiting shareholder payouts.
Shares of the big drugmaker fell sharply after it projected a dip in full-year adjusted profits per share on roughly flat revenues.
Pfizer expects 2026 revenues of between $59.5 billion and $62.5 billion, compared with $62 billion in 2025.
The pharma giant last month completed an acquisition of biotech firm Metsera, deepening its portfolio of products in the fast-growing market for weight loss drugs.
Pfizer has also identified oncology as a major growth area, while Chief Executive Albert Bourla insisted the company would continue to invest in vaccines in the face of recent controversial policies under the vaccine-skeptic Trump administration.
The drugmaker expects a drop of $1.5 billion in 2026 revenues tied to lower Covid-19 sales and the decline of another $1.5 billion from products experiencing a loss of exclusivity.
Pfizer has maintained a dividend but not undertaken share repurchases in 2025. Executives said they would continue to steer cash into development programs rather than stock repurchases.
"Obviously I would love to do share repurchases," Chief Financial Officer David Denton said on a conference call. "The reality is at this point in time, I think the best and highest use of capital is continued investment in business development."
Briefing.com said the results underscored Pfizer's "painful transition" out of the Covid-19 era.
The tepid outlook "indicates that earnings will likely remain stagnant or decline slightly as the company digests the Metsera deal and ramps up R&D," Briefing.com said in its note.
On vaccines, Bourla characterized recent policy shifts under US Health Secretary Robert Kennedy as misguided.
"Vaccines are an essential part of any health care system," Bourla said. "We will continue investing in vaccines because ... this is an anomaly that will correct itself. I hope pretty soon."
Under Kennedy, an appointee of Donald Trump, the Centers for Disease Control recently revised its website with language that undermines its previous, scientifically grounded position that immunizations do not cause autism.
Bourla has also touted a deal announced in September with the Trump administration in which the company promised to lower some drug prices in exchange for a three-year reprieve on planned tariffs.
Shares of Pfizer fell 3.8 percent in afternoon trading.
P.Costa--AMWN