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Drugs giant AstraZeneca reveals higher profits, savings plan
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China denies spying on Nvidia's Jensen Huang
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French economy 'headed for a wall' as GDP shrinks
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BP net profit quadruples on higher oil prices
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South Korea to prosecute students cheating with smart glasses
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Kiss backs 'hungry' Beale to push for Wallabies game time
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Surging costs of living top US voter concerns
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World number one Rybakina withdraws in Tokyo with injury
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Basic services, fading loyalties loom over South Africa's vote
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Malawi's fuel shortages, record prices deepen economic crisis
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Shock, vindication, regret: Scientists react to AI roiling life's work
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Rubio hosts G20 ministers as Iran, Ukraine wars divide members
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Crypto platform Binance confirms $6.3 bn hack
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From minerals to AI, EU and Canada to forge new alliance
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Boozer shines as Grizzlies top Blazers in battle of NBA unbeatens
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Fire pollution killed 3,560 people in Indonesia in September: report
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Jorge Martin confirmed to race at Malaysian MotoGP
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Ian Wright and Jamie Carragher split on Liverpool-Arsenal prediction
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Bayern and Kane host Dortmund after week of 'extremes'
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The Duskbloods delayed as Nintendo Switch 2 release moves to 2027
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Packers beat Panthers 27-19 as Watson returns from hospital
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Russia turns to NATO countries for prosthetics amid war-related shortages
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Affordable supermarket fashion offers designer-inspired autumn alternatives
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Researchers on island encounter giant spider legs emerging from a burrow
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Judge throws out Australian mushroom killer's appeal, imposes harsher sentence
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Britain's King Charles lands in ex-colony Guyana
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Pelicans down Kings for first win of NBA season
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Arsenal assess Bukayo Saka fitness concerns before Liverpool meeting
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Tech firms take fresh hit as earnings misses fan AI fears
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£10,000 garden project transforms a UK home into a miniature Greece
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Worcestershire leaders back renewed two-unitary council reorganisation
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Forest destruction tests Armenia-Azerbaijan peace push
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India's animal megacentre vows reset after criticism
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Deal still eludes nations on final day of UN nature talks
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Dodging fuel price hikes, Damascus drivers turn to electric cars
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Teen rallies take to the streets across Italy
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Alvechurch manager praises resilience but seeks improvement after Anstey draw
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Netanyahu bloc finishes ahead in Israel vote, but well short of majority
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Crypto platform Binance confirms major hack, more than $2.5bn frozen
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Rural US hospitals, collateral victims of Trump politics
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Sports chiefs face losing battle to keep sport separate from politics
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How Trump could interfere in US midterm elections
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Nvidia's web of AI bets: smart strategy or bubble risk?
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As Republicans downplay abortion for midterms, four US states to vote
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Carrick fights for Man Utd job, Arsenal face Liverpool test
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No. 4 Indiana looks to revive offense against improving Minnesota
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Apple TV crime drama Nocturne brings a Scandinavian thriller to Pennsylvania
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Police close investigation into Hayden Panettiere death after coroner ruling
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Charity crowdfunds millions to buy historic English estate
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Australian mushroom killer loses appeal, has sentence extended
Crude back above $110 on Strait stalemate as US stocks retreat
Oil prices jumped on Tuesday to their highest level since the US-Iran ceasefire, pressuring US stocks as lack of progress on an accord to reopen the Strait of Hormuz added to inflation worries.
Meanwhile, tech stocks took a hit and investors turned their attention to corporate earnings and the outlook for interest rates.
Efforts to end the Middle East war appeared at a standstill on Tuesday, with the United States considering Tehran's latest offer to unblock the strait, and Iran saying Washington could no longer dictate terms.
Iran has blockaded the waterway -- a vital conduit for oil and gas shipments -- since the start of the US-Israeli offensive two months ago, sending shockwaves through the global economy.
CNN, however, reported that US President Donald Trump was unlikely to accept Iran's proposal to restore traffic in the strait, as Qatar warned of the possibility of a "frozen conflict" if a definitive resolution is not found.
Oil prices rallied, with Brent crude for June delivery rising 2.8 percent to $111.26 a barrel.
The benchmark US contract, WTI for June delivery, rose 3.7 percent to $99.93 per barrel.
Hopes for a deal had been rising going into last weekend but Trump dashed them on Saturday by scrapping a planned trip by his envoys Steve Witkoff and Jared Kushner to Islamabad for negotiations.
"Right now, the market is not optimistic about the chance of a deal to reopen the Strait due to Iran's request to push discussions about nuclear disarmament into the future," said Kathleen Brooks, research director at XTB trading platform.
Meanwhile, major crude producer United Arab Emirates announced it will withdraw from the OPEC and OPEC+ oil cartels on May 1, calling it a strategic decision.
Rystad Energy analyst Jorge Leon said the UAE's move is significant as, alongside Saudi Arabia, it is one of the few nations with significant spare production capacity.
"While near-term effects may be muted given ongoing disruptions in the Strait of Hormuz, the longer-term implication is a structurally weaker OPEC" and potentially more market volatility, Leon said.
- AI concerns -
The tech-heavy Nasdaq Composite fell nearly one percent, with shares in companies linked to OpenAI hit by a report in the Wall Street Journal that the ChatGPT maker had missed targets on the number of users and revenue.
Shares in Oracle, which is building massive data center capacity for Open AI, fell more than four percent, while CoreWeave, another important OpenAI provider, sank 5.8 percent.
When you get a piece of news like this, you know, people say, 'Oh, maybe I'll just take profits and see what happens,'" said Thomas Martin at Globalt Investments. "This is going to continue to go on for quite a long time."
The news also means that AI spending by tech giants Amazon, Google, Meta and Microsoft will come under even closer scrutiny when they report results later this week.
Europe's main equity markets ended mostly lower.
Stock markets mostly fell in Asia, under further pressure after the Bank of Japan sharply raised its inflation forecasts for the current year and halved its growth projections owing to surging oil prices while leaving its key interest rate unchanged.
The US Federal Reserve began a two-day meeting Tuesday amid the same growing inflationary concerns over the surge in energy costs. However, the US central bank is expected to keep rates unchanged.
- Key figures at 2010 GMT -
West Texas Intermediate: UP 2.8 percent at $111.26 a barrel
Brent North Sea Crude: UP 3.7 percent at $99.93 a barrel
New York - Dow: UP 0.1 percent at 49,141.93 (close)
New York - S&P 500: DOWN 0.5 percent at 7,138.80 (close)
New York - Nasdaq Composite: DOWN 0.9 percent at 24,663.80 (close)
London - FTSE 100: UP 0.1 percent at 10,332.79 (close)
Paris - CAC 40: DOWN 0.5 percent at 8,104.09 (close)
Frankfurt - DAX: DOWN 0.3 percent at 24,293.56 (close)
Tokyo - Nikkei 225: DOWN 1.0 percent at 59,917.46 (close)
Hong Kong - Hang Seng Index: DOWN 1.0 percent at 25,679.78 (close)
Shanghai - Composite: DOWN 0.2 percent at 4,078.64 (close)
Euro/dollar: DOWN at $1.1712 from $1.1721 on Monday
Pound/dollar: DOWN at $1.3515 from $1.3535
Dollar/yen: UP at 159.64 yen from 159.42 yen
Euro/pound: UP at 86.64 pence from 86.60 pence
burs-jmb/sla
T.Ward--AMWN