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US envoys hold 'important' talks in first trip to Kyiv
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Everton shrug off transfer window woes to hold Man Utd
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Championship leader Antonelli wins Italian Grand Prix
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'Nothing has changed': FIFA confirms Infantino to run for re-election
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Vardy signs for Championship strugglers Burnley
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UN's Nepal chief makes emotional plea for flood-ravaged country
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FIFA confirms Infantino will run in presidential election
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Italian GP red-flagged after massive Leclerc crash
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With joy and grief, Palestinian football marks return
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US envoys hold talks with Zelensky on first Kyiv visit
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Iran threatens greater force if US launches more attacks
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'Truly scared': Blazes outpace firefighters in Indonesian Borneo
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Vandals uproot Berlin tree commemorating Pride attack victims
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German director Wenders clarifies views on film and politics
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Trump envoys arrive in Kyiv for first Ukraine visit
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Nepali rescuers buoyed by miracle finds but tough conditions persist
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Indonesia's main airport suspends operations after volcanic eruption
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At last: Straight sets win over Tabilo puts Zverev in US Open last 16
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US aircraft carrier departs Thailand after port call
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Jovic 'loses sanity five times over' to oust friend Eala in US Open epic
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Haze emergency grips Malaysian Borneo town
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China's memories of Mao fade to nostalgia 50 years after his death
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Messi creates both Miami goals in 2-2 draw with Atlanta
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US envoys discuss with Putin 'substantive' plans for steps to end Ukraine war
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Rybakina books US Open fourth-round berth, inches closer to No. 1
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Zheng stuns Keys as US Open upsets dim American hopes
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Sobering reality: Curbs on alcohol in northeast Syria cause discontent
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Jovic 'loses sanity five times over' to oust Eala and book Gauff clash
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Wobbly Osaka 'shocked' to battle past Mertens and reach last 16
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'Like a jewel': Japan's luxury ice revered by bars worldwide
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Argentina 'let off hook' by Australia as Kiss's winning run ends
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Kiss's winning run ends as Argentina hold Australia to draw
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Alcaraz excited to face 'dangerous' Paul for US Open quarter-final berth
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Gauff into round four at US Open after straight-set win
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Prince William to represent King Charles III at Norway late King Harald's funeral
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Bordeaux hammer Racing in Top 14 start as Bielle-Biarrey extends deal
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Inter and Roma roar back to win thrillers and share top spot
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Zheng, Potapova pull off upsets to reach US Open last 16
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Swiatek into US Open fourth round in tight two-setter
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AFP photographer wins top prize for Madagascar protest coverage
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Werro wins in Brussels, as Russell and Dos Santos shine
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Keys: 'I felt like I couldn't play tennis'
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Kolbe breaks jaw and shoulder injury sidelines Savea
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Simmonds stars as Pau upset Montpellier
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US military strikes oil tankers as Iran vows tougher reprisals
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Inter roar back in five-goal thriller with Napoli
Novartis acquiring US firm Avidity Biosciences for $12 bn
Swiss pharmaceutical giant Novartis announced Sunday it had agreed to buy Avidity Biosciences, with the San Diego-based biopharmaceutical company being valued at $12 billion.
"The proposed acquisition is expected to create an industry-leading pipeline, building on the Novartis expertise in spinal muscular atrophy and commercialisation capabilities in genetic neuromuscular diseases," Novartis said in a statement.
The deal is expected to close in the first half of 2026, after Avidity's early-stage precision cardiology programmes has been separated off into a new company.
Avidity common stock holders will receive $72 per share in cash when the deal closes -- a 46-percent premium on Friday's closing share price, Novartis said.
The deal values the company "at approximately $12 bn on a fully diluted basis and representing an enterprise value of approximately $11 bn at the expected closing date", it added.
Avidity Biosciences develops Antibody Oligonucleotide Conjugates (AOCs) to treat serious diseases, with an initial focus on rare neuromuscular genetic disorders.
"Avidity's pioneering AOC platform for RNA therapeutics and its late-stage assets bolster our commitment to delivering innovative, targeted and potentially first-in-class medicines to treat devastating, progressive neuromuscular diseases," said Novartis chief executive Vas Narasimhan.
"The Avidity team has built robust programmes with industry-leading delivery of RNA therapeutics to muscle tissue," he added.
"We look forward to developing these programmes to meaningfully change the trajectory of diseases for patients."
Pharmaceutical companies are facing massive pressure from US President Donald Trump's administration to move production to the United States.
Novartis, based in Basel in northern Switzerland, announced in April that it planned to invest $23 billion in the United States over five years.
F.Schneider--AMWN